Why Patients Refuse to Join a Clinical Trial and What Sponsors Can Do About It.

Jonathan Eilberg • December 16, 2023

Many people hesitate or refuse to enroll in these studies, posing a challenge for researchers and medical professionals. Understanding these hesitations and the role of patient recruitment agencies can help improve subject enrollment in research studies.

Reasons for Hesitation or Refusal in Clinical Trial Enrollment

1. Lack of Awareness - Many people are simply unaware of ongoing clinical trials or their eligibility to participate. This lack of awareness can stem from a limited understanding of the trial's purpose, benefits, or safety. Educating the patient is critical particularly when they are in the mist of a healthcare challenge where an clinical trial would benefit them. Not everyone has the fortitude to struggle through the clinicaltrials.gov listings. This is why an easy to comprehend, custom clinical trial website explaining the study is so critical.


2. Misconceptions and Fears - There are some genuine concern, particularly with African Americans, when it comes to the history of clinical trials. Medical experimentation including the infamous Tuskegee Syphilis Study shook the black community to the core. Mistrust in the medical system, often rooted in historical abuses in medical research, can be a significant barrier, particularly in minority communities. Common fears for everyone include the risk of side effects, the use of placebos, or the belief that they might receive inferior care during the trial. Misinformation and misconceptions about clinical trials can deter potential participants as well.


3. Accessibility Issues - Geographical distance from the trial site, lack of transportation, and time commitment are significant barriers. Moreover, the complex language often used in trial descriptions can be a hurdle. Sponsors need to stop using their clinicaltrials.gov listing as the sole source of their study, especially if their conducting patient recruitment marketing to promote a trial.


Role of Patient Recruitment Agencies in Improving Enrollment

Patient recruitment companies, like Trial AMPlify, play a vital role in addressing these challenges. Here’s how they can make a difference:


1. The Importance of Creating Dedicated Clinical Trial Websites Clinical trial websites serve as a central hub for information,

making it easier for potential participants to find and understand trials. They can offer detailed descriptions, eligibility criteria, and direct contact options. These trial study sites can also influence the patient's inner circle, advocacy groups and physicians.


It Only Takes One Person to Scare a Patient Out of Participating in a Clinical Trial. Sponsors need to Recruit Differently.



2. Utilizing SEO and Google Ads
- By optimizing content for Google page #1 results (SEO) and using targeted Google ads, patient recruitment agencies can increase the visibility of clinical trials overnight. Google ads can appear instantly and drive study enrollment while SEO takes hold. This approach ensures that when people search for related information, they find relevant trial options.


3. Engaging Through Social Media Platforms like Facebook - Social media campaigns can raise awareness and address misconceptions. Platforms like Facebook allow for targeted advertising and community engagement, reaching a broader and more diverse audience.


4. Physician Outreach - Agencies can collaborate with physicians to identify eligible patients within their practices. Physicians can provide trusted information and encouragement to patients, significantly influencing their decision to participate. As a side note - Trial AMPlify has access to over 400K physicians world-wide. This list of physicians can be customized for physician outreach marketing campaigns based on specific geo's and practice specialty. 


5. Building Trust and Awareness - Continuous efforts to educate the public, addressing common fears and misconceptions, and building relationships with community leaders and patient advocacy groups can enhance trust.


Summary

The reluctance to enroll in clinical trials is a multifaceted issue, but with the strategic use of dedicated websites, SEO, online advertising, social media platforms, and physician outreach, patient recruitment agencies can play a transformative role. By increasing awareness, dispelling myths, and making trials more accessible and understandable, these agencies can significantly contribute to the advancement of medical research and patient care.

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Trial AMPlify, a patient recruitment company located in Boston, MA is focused on increasing subject enrollment differently. We are solely focused on global clinical trial marketing, customized physician outreach campaigns, and world-class clinical trial website design for Biotech, Life Science and Pharma firms. If you would like to see our dedicated clinical trial website and patient recruitment campaigns in action, feel free to reach out to us.

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